New advances in infrared spectroscopy

New advances in infrared spectroscopy offer improved spatial resolution, say researchers

Three research papers exploring the use of infrared spectroscopy, both through label-free mid-infrared spectroscopic imaging (MIRSI) and optical photothermal infrared (O-PTIR) spectroscopy, have led to exciting advances in their fields. 

The research establishes the potential for these advanced techniques to investigate bone composition with submicron spatial resolution, offering a clearer insight into the structure of collagen and other bone minerals. This has real-world applications in improving the diagnostic accuracy of myelofibrosis (MF), as well as bolstering our understanding of the progression of the disease. 

Read the full research papers here:  

Polarization sensitive photothermal mid-infrared spectroscopic imaging of human bone marrow tissue, Rupali Mankar et al. 

Application of optical photothermal infrared (O-PTIR) spectroscopy to assess bone composition at the submicron scale, Emily Reiner.

Matrix/mineral ratio and domain size variation with bone tissue age: A photothermal infrared study, Taeyong Ahn et al.