New advances in infrared spectroscopy
New advances in infrared spectroscopy offer improved spatial resolution, say researchers
Three research papers exploring the use of infrared spectroscopy, both through label-free mid-infrared spectroscopic imaging (MIRSI) and optical photothermal infrared (O-PTIR) spectroscopy, have led to exciting advances in their fields.
The research establishes the potential for these advanced techniques to investigate bone composition with submicron spatial resolution, offering a clearer insight into the structure of collagen and other bone minerals. This has real-world applications in improving the diagnostic accuracy of myelofibrosis (MF), as well as bolstering our understanding of the progression of the disease.
Read the full research papers here:
Polarization sensitive photothermal mid-infrared spectroscopic imaging of human bone marrow tissue, Rupali Mankar et al.
Application of optical photothermal infrared (O-PTIR) spectroscopy to assess bone composition at the submicron scale, Emily Reiner.
Matrix/mineral ratio and domain size variation with bone tissue age: A photothermal infrared study, Taeyong Ahn et al.