In recent years X-ray Micro Computed Tomography (CT) has become established in the pharmaceutical industry as a vital analytical tool, enabling significant advances in product development, quality control and packaging.
Bruker’s SkyScan micro-CT instruments have been adopted by the world’s leading pharma companies, as well as academic research groups. They combine class-leading resolution and performance, with easy-to-use workflows.
Non-destructive 3D internal imaging – see inside your sample
Applications
Micro-CT, also referred to as X-Ray Microscopy (XRM), is widely used in areas such as:
Tablet Development
- Compaction density (porosity, pore size, distribution)
- Identify stress-induced micro-cracks
- Measure coating thickness and uniformity
- Distribution of active ingredients (total volume and percent volume)
- In-situ compression testing
Packaging & Sealing
- Seal integrity – locate gaps and leaks
- Compare changes to optimise your processes
- Measure component variation from your suppliers
Final Product Inspection
- Check component alignment – without opening the packaging
- Detect defects
- Quantitative 3D measurements
- Pre- and post- usage performance tests
- High throughput scanning of medical devices
Failure Analysis
- Non-destructive investigation – see where and how the failure occurred
- Root cause analysis
- Archive digital information
![Micro-CT scan of coatings on a pharmaceutical drug](https://blue-scientific.com/wp-content/uploads/micro-ct-pharmaceutical-drug.jpg)
Tablet scanned with the Bruker SkyScan 2214
![Medical Inhaler](https://www.blue-scientific.com/wp-content/uploads/medical-inhaler.jpg)
Inhaler scanned with the Bruker SkyScan 1275
![Pharmaceutical Syringe](https://www.blue-scientific.com/wp-content/uploads/syringe-imaging.jpg)
Syringe scanned with the Bruker SkyScan 1275
![Bruker Micro-CT Pharmaceuticals Brochure](https://blue-scientific.com/wp-content/uploads/micro-ct-pharma-brochure.jpg)
Micro-CT for the Pharmaceutical Industries Brochure
![Tablet](https://www.blue-scientific.com/wp-content/uploads/pharma-tablet.jpg)
Left: Paracetamol tablet – colour-coded by coating thickness. Taken with the Bruker SkyScan 1272.
![Bruker Micro-CT Sample Changer](https://www.blue-scientific.com/wp-content/uploads/bruker-skyscan-sample-changer.jpg)
High-throughput Micro-CT with a Sample Changer
Automated scanning to save time. Ideal for comparing large numbers of samples and for quality control.
![Pharmaceutical Tablet](https://www.blue-scientific.com/wp-content/uploads/pharmaceutical-tablet.jpg)
![Micro-CT Scan of a Tablet](https://blue-scientific.com/wp-content/uploads/skyscan-live-lab-2-1024x561.jpg)
Recorded Live Stream: An Inside Look at Pharmaceuticals and Medical Devices
See how X-ray microscopy’s used for non-destructibe product inspection and QA of pharmaceuticals and medical devices in Bruker’s live stream – available to watch on YouTube. The stream includes demos, discussion and more:
Bruker XRM Instruments
Blue Scientific is the official distributor of Bruker X-Ray Microscopy instruments in the UK, Denmark, Finland, Sweden, Iceland and Norway. We’re here to advise on which system would suit your research, and we also offer service and support.
![Bruker SkyScan 1275 Micro-CT](https://www.blue-scientific.com/wp-content/uploads/bruker-skyscan-1275-small.jpg)
Bruker SkyScan 1275
Fast, self-optimising benchtop scanner. High quality scans at the press of a button.
![Bruker Skyscan 1272](https://blue-scientific.com/wp-content/uploads/1272.jpg)
Bruker SkyScan 1272
Sub-micron resolution from a benchtop system. World’s first scanner with >200Mp in each cross-section.
![Bruker SkyScan 2214](https://www.blue-scientific.com/wp-content/uploads/bruker-skyscan-2214.jpg)
Bruker SkyScan 2214
Multi-scale nano-CT for the widest range of object sizes/ resolutions.